To start your a new game of Civilization VI, you can select your preferred game mode of either a Single Player or a Multiplayer campaign from the main menu. 

Single Player:
- Play Now: Selecting this begins the game immediately. It will being a game on a preset of ""Small Continents"" as your map, ""Prince"" difficulty, ""Standard"" game speed, and with a randomly chosen leader.
- Scenarios: A special game mode comes with unique settings, objectives, rules, and leaders that are distinct from the standard game. This provides an experience that is focused on historical events or specific themes.
- Create Game: This lets you customize your game by choosing a variety of settings such as ruleset, leader, game speed, map type, map size, and difficulty level. Beginners might start on a smaller map with a lower difficulty to get accustomed to the game mechanics.

Multiplayer:
- Local Network: Lets you play with up to 4 players in the same network.
- Hot Seat: Lets you play with up to 6 players taking turns on the same device.

Tutorial:
- For those new to Civilization 6, we recommend starting out with the tutorial. It is here that we begin our journey of raising an empire from humble beginnings to greatness! Play as Cleopatra or Gilgamesh as you write your own version of history."