Oxenfree features a cast of intriguing characters, each contributing to the game's narrative:

Alex: The main character. Her decisions are central to the game's unfolding events.

Jonas: Alex's new stepbrother, Jonas is initially reserved but becomes a key ally as the island's mysteries unfold. Players can influence his relationship with Alex.

Ren: Alex's best friend, Ren is easygoing and humorous, often providing comic relief. Despite his laid-back demeanor, he cares deeply about his friends.

Clarissa: Michael's ex-girlfriend, Clarissa is often antagonistic towards Alex due to their shared history. Her sharp exterior hides her struggles with grief.

Nona: A quiet and thoughtful friend, Nona is caught between the group's conflicts. Her presence brings a sense of calm, and her interactions can alter group dynamics.