Oxenfree II: Lost Signals features a cast of intriguing characters, each contributing to the game's narrative:

Riley: The protagonist. An environmental researcher returning to her hometown of Camena, drawn into mysterious events involving unusual radio signals.

Jacob: Riley's companion. A high school acquaintance of Riley who has remained in Camena and assists in unraveling the island's mysteries.

Olivia: A key character in the story. Olivia's role and motivations add complexity to the narrative, influencing the direction of Riley’s journey and the unfolding mysteries.